
Siamak Bahram
@6p21_3
A Major Histocompatibility Complex (MHC)-centric view of life
ID: 1093603634372362240
07-02-2019 20:13:19
29 Tweet
26 Followers
2 Following

Almost 30 years after discovery of MICA (pnas.org/doi/abs/10.107…) evidence for its formal recognition as a histocompatibility antigen in solid organ transplantation. #transplantation #HLA #histocompatibility Inserm @InsermEst CHRU Strasbourg - Nature Medicine


Mismatches in the #MICA locus and the presence of anti-MICA donor-specific antibodies are associated with reduced graft survival and increased #kidney rejection Carapito Raphaël Siamak Bahram Inserm - CHRU Strasbourg nature.com/articles/s4159…

MICA in kidney #transplants ow.ly/cl4Q50ILcQE Nature Reviews Nephrology









Pr Bahram Siamak Bahram lauréat du prestigieux financement European Research Council (ERC) pour son projet qui vise à identifier la totalité des gènes d’histocompatibilité : une quête inachevée depuis près d’un siècle. chru-strasbourg.fr/pr-bahram-laur…


👍Pr Seiamak Bahram Siamak Bahram (directeur de l'unité 1109 Inserm @InsermEst /Université de Strasbourg, chef de service du laboratoire d’immunologie CHRU Strasbourg) remporte le prestigieux financement européen European Research Council (ERC) Advanced Grant ➡️crbs.unistra.fr/actualites/act…



Just out ! Multiyear, multiteam effort from structural biology to clinical medicine | A pleiotropic recurrent dominant ITPR3 variant causes a complex multisystemic disease | Science Advances science.org/doi/10.1126/sc… Inserm @InsermEst CHRU Strasbourg Science Advances

Check out our latest tiny foray in the world of gene mutations (ITPR3) related to #immunodeficiencies. Katerina Jerabkova-Roda (post-doc) & @ignaciobusnelli (ex-EM expert) helped the team of S.Bahram showing how such mutation perturbs IP3R3 localization in patient fibroblasts.


