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📢📢Always wanted to look at all expressed genes in whole E8.5/9.0 mouse embryos, at near single cell resolution while keeping the 3D spatial information🤓? Worry no more, Abhishek Sampath Kumar, Luyi Tian 田鲁亦 & Adriano Bolondi, PhD got you covered with their latest study. nature.com/articles/s4158…

🚨Paper alert🚨 With Abhishek Sampath Kumar, Luyi Tian 田鲁亦 & Guignard Lab we built a 3D spatial transcriptomic atlas of mouse embryos to identify gene expression patterns across tissues. Fei Chen Lab #MeissnerLab @MPIMG Broad Institute A🧵(1/8). nature.com/articles/s4158…

New research in Nature Genetics presents an experimental and computational framework for the spatiotemporal investigation of whole embryonic structures and mutant phenotypes. Abhishek Sampath Kumar Fei Chen Lab nature.com/articles/s4158…

Check out how sc3D can be used to reconstruct, visualize and analyze 3D spatial gene expression patterns from other datasets (such as Stereo-seq) Guignard Lab BGI Group

This week’s #FluorescenceFriday user is Abhishek Sampath Kumar! Abhishek Sampath Kumar applied #HCRimaging to confirm the expression patterns of well-known lineage-defining markers in the mouse neural tube. Check out his latest publication here: doi.org/kmdc

Check out this really exciting work from Arlotta Lab Noelia Antón-Bolaños @Irene_Faravelli and team. The multi-donor chimeroid with various genetic backgrounds is a great platform for scalable testing of genetic susceptibility to neurotoxic triggers.

Join us on the 1st of November to learn about our efforts in reconstructing 3D spatial transcriptomic maps of whole mouse embryos.

Register now to attend the webinar on the 1st of November. We’ll discuss our efforts in reconstructing 3D spatial maps and using it to understand tissue patterning in the embryo.

I am excited to share the final version of this work published today in Nature Cell Biology. A great collaboration with Liat,Edda Schulz and the entire team MPI for Molecular Genetics

A fantastic and systematic study from Maximilian Stötzel Aydan Bulut-Karslioglu ! Kudos to Maximilian Stötzel for his hardwork, dedication and success. Happy to have contributed. Congratulations to all the authors MPI for Molecular Genetics

In the multi-donor brain chimeroids, we also show that the different donor lines are spatially distributed, profiled with Curioseeker Curio Bioscience . Excited to have contributed to this tremendous work led by Noelia Antón-Bolaños Irene Faravelli Arlotta Lab. Congratulations to all authors.

First one out from Luyi Tian 田鲁亦 lab in Nature Methods congratulations to all authors. Happy to have contributed.

Check out this amazing work from Philine Jesse Engreitz , answering an important question on how 3D contacts tune enhancer effects on gene expression. Congratulations to the entire team.