🤩Plz RT🤩 Assist/Assoc. Prof. Position job open at Lunenfeld/UofToronto in Computational #Virology/#Genomics. Toronto is reaching critical mass in #microbiology #bioinformatics Let's make it happen! #AcademicTwitter #AcademicCareer Future PI Slack 🏹🎯 nature.com/naturecareers/…

Tenure track Professor of Teaching position open in my department. recruit.ucdavis.edu/JPF06676

Now that we're entering faculty job season, I want to reshare my ✨job search advice doc✨. It compiles all the super helpful advice I received from mentors & includes my own experiences on the market. Best of luck out there, everyone - you got this! 💪 helpimascientist.com/wp-content/upl…

6 main figs and 5 supplementary figs .

Cool paper describing the discovery of bacteria that adhere to the intestinal cells of C. elegans biorxiv.org/content/10.110…

APEX peroxidase is a versatile tool for proximity labeling and electron microscopy (EM) but its requirement for toxic H2O2 is a liability. We now report LaccID, a multicopper oxidase evolved from an ancestral fungal laccase that oxidizes aromatic substrates using non-toxic O2

The master bank of our CRISPR libraries consists of >22,000 bacterial glycerol cultures. My coworker Ilan Margalith studied the impact of temperature (-80°C vs -20°C), glycerol (15% vs 50%), and freeze-thaw cycles (1x vs 30x) onto viability. Results: chatgpt.com/share/6733819e…

I am very skeptical of the AI/ML/computational methods to predict protein-protein interactions. Prove me wrong. I present a challenge for anyone who claims they can predict protein-protein interactions. 1/n

This is like AlphaFold, but for protein localisation rather than folding It's a deep learning model that predicts a protein's subcellular compartment based on its amino acid sequence alone:

Really cool work from Andy Fraser! Converting metabolite abundance into barcode abundance with aptamers. Smol-seq is the best -seq!

What happens to bacterial genomes when they're cloned into yeast? Do they transcribe, do they get silenced, do they get packaged away from the rest of the DNA? This cool study congrats to the Koszul lab team at Pasteur for this great work science.org/doi/10.1126/sc…

Marchantia polymorpha - as per its name occurs in many forms. We & many researchers have joined to study the genetic forms and adaptations of this liverwort led by Chloé Beaulieu, Pierre-Marc Delaux and Maxime Bonhomme LRSV. nature.com/articles/s4158… Image David Hoey

We are ready to recruit new postdocs to join our team at MPI Biology Tübingen! Please help us spread the words. Thank you!!! 😊

Very excited to see my first first author paper published in PNASNews . We found the first effector regulator in plant-parasitic nematodes! Congratulations to all authors and co first author Clément Pellegrin. pnas.org/doi/10.1073/pn…

Butterfly populations across the U.S. are in alarming decline, according to a new Science study, with total abundance falling by 22% in just 20 years. Such widespread and worrisome losses portend broader environmental threats and emphasize the urgent need for conservation

Forty New Genomes Shed Light on Sexual Reproduction and the Origin of Tetraploidy in Microsporidia biorxiv.org/content/10.110… #biorxiv_genomic

“Don’t pick the wrong animals, it’s sad” #worm25

Many of the most complex and useful functions in biology emerge at the scale of whole genomes. Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵