TIL that E. coli K12 — the most widely used strain of bacterium for biological research — is named "K-12" because it was first isolated from a diphtheria patient staying in room K-12 of a Stanford University hospital in 1922. Naming conventions in biology are weird!

Bacterial cell wall, biofilm and morphology enthusiasts - our new preprint shows how E. coli manages to survive without its essential cell wall! Check it out 👇#microbiology #bacteria LeidenBiology The Claessen Lab Han de Winde @handewinde.bsky.social

Streptococcus pneumoniae epidemiology, pathogenesis and control Henriques-Normark & co. explore recent insights into Streptococcus pneumoniae epidemiology, clinical disease and pathogenesis, as well as new treatment and prevention approaches Henriques-Normark lab rdcu.be/dZqzB

How do mitochondria, the cell’s energy-producing organelles, perform competing metabolic processes? Segregation into distinct populations — one that makes energy-storing ATP molecules and one that does not — could explain it nature.com/articles/d4158…

SUCROSE SELECTION IS WORKING!!!! cscA flask has the sucrose invertase overexpressing. CscB flask has only the sucrose permease. Heavy innoculum on both sides so any slight cloudiness is due to initial innoc and trace LB from scooping. HUGE MILESTONE!!!

#weekendreading 📑🔬 Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis Cell Metabolism cell.com/cell-metabolis…

You want to run antibiotic MICs according to best-practice clinical microbiology protocols, but you are not sure how? Our article will walk you through it all! Great to work with Nikol Ayesha Mahmood and a pleasure to publish in npj Antimicrobials and Resistance. rdcu.be/dZp04 #AMR

A bacterial cell wall repair and modification system to resist host antibacterial factors biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Characterization of a GpsB-associated regulator of PBP1a reveals the organization of the cell wall remodeling complex of ... biorxiv.org/cgi/content/sh… #biorxiv_micrbio

I had some help 🎶 Teamwork makes the dream work! Checkout our latest preprint spearheaded by Jessica Burnier in a great collab with the labs of Waldemar Vollmer, ᐯIᑕTOᖇ ᑎIᘔET & Malcolm Winkler biorxiv.org/content/10.110…

Great new work from the groups of Khaled A. Selim , Michael Galperin , and David Dubnau! ComFB is a c-di-GMP and c-di-AMP binding protein family! #subtiwiki biorxiv.org/content/10.110…

New preprint! A new direction for my research program: Bacteria can use antagonism to forage for nutrients in microbial communities. Shoot spearguns with toxins into other cells and leak out nutrients! biorxiv.org/content/10.110…

The freshness and engagement levels over there:

1/8 Publication Alert! Delighted to share the publication of a collaboration by Gerben Marsman (Arturo Zychlinsky lab Max Planck Institute for Infection Biology) and Xuhui Zheng (former PhD student in my lab) et al detailing how Histone H1 kills MRSA (cell.com/cell-reports/f…).

The end of a long standing chapter - happy to see the latest contribution from my PhD Lecuit Lab out! Institut Pasteur, since 1887 Cell Biology & Infection Learning Planet Institute Université Paris Cité Many thanks to everyone who contributed - colleagues, friends, and family included!

📢 Historic day for Portugal and phage therapy! 🇵🇹 A framework was approved, allowing magistral preparation of personalized phage products. 🙌 Grateful to Jean-Paul Pirnay, my group Azeredo Lab Portuguese patients, and doctors who signed a petition inspired by the Belgium model.

#HappyNewYear2025 ! A globally positive year for me (one great publication plus some rejected grants), as 2024 reaches its epilogue, I want to wish a successful 2025 to my scientific colleagues and collaborators. Eager to read your newest epic findings in the next 12 months!

One day... 🥉🥈🥇🏆